A Complete Description of the Drug

Sildenafil: A Complete Description of the Drug – Learn about Sildenafil in the treatment of erectile dysfunction

Sildenafil – the most purchased means of excitement around the world. Buy Sildenafil effectively combats erectile dysfunction in men and maintains penile hardness sufficient for sexual intercourse. It has a beneficial effect on blood circulation in the pelvic area, which contributes to the expansion of blood vessels.

It provides excellent results even with serious pathologies such as spinal cord injuries, prostate surgery, diabetes and other diseases that negatively affect sexual function. Broad popularity and sales statistics in pharmacies confirm the high effectiveness of the drug to eliminate sexual problems.

Since 1977, American pharmacologists have been working on the development of a substance that can reduce and expand blood vessels in the heart, brain and lungs. This lasted until 1992, the year that scientists began testing Sildenafil citrate. However, until then there were no noticeable results from their work. The tests were conducted with the aim of making a drug for the treatment of diseases of the cardiovascular system.

Sildenafil citrate exhibited the unexpected property of blocking certain enzymes. This led to a dilation of blood vessels in the area of ​​the urogenital system. The substance caused a sustained and prolonged erection, which pleasantly surprised the men who participated in the tests.

The substance was then examined in a different direction. As a result, all known Viagra tablets appeared in 1998. In the same year buy sildenafil three scientists received the Nobel Prize for setting up a medicine for the treatment of heart and lung diseases. The makers of Viagra had developed a medicine with Sildenafil that would prove to be groundbreaking.

Application and composition

Sildenafil is released in the form of citrate. Shelf life is 2 years.

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The most important form of release – tablets, dosing the active ingredient in 25 mg, 50 mg or 100 mg. In classic Viagra, the tablets have a diamond-shaped, convex shape and the pills are covered with a recognizable blue coating. Parallel to the drug, a wide range of which is available, are not only produced in tablets, but also in the form of powder, capsules (100 mg) and drops. In one package Sildenafil can be 1 to 12 tablets packed.

In addition to the basic substance, the preparation contains auxiliary components such as povilone, cellulose, magnesium stearate, lactose monohydrate and some other ingredients.

Description of the medicine’s effect

Sildenafil is classified as a selective inhibitor of PDE-5 (type 5 phosphodiesterase). The principle of its action is based on the dilation of blood vessels in the sexual organs and the increase in blood flow to the penis. 

This makes it possible for men to get a good and long erection. Buying Sildenafil can eliminate erectile function problems, which manifest itself in the penis’s inability to maintain the necessary hardness for sexual contact. This effect of the drug is due to its sildenafilability to influence the enzymes responsible for achieving an erection of the penis.

As mentioned earlier, however, tablets cannot stimulate an erection themselves if there is no sexual attraction to the partner. If there is a natural desire, the excitement increases and Sildenafil will be able to provide excellent support.

The drug restores the lost response to sexual arousal. Normal erections are impossible without the release of nitric oxide into the penis’s swelling bodies, which activate the enzyme guanylate cyclase. Its activation involves an increase in the level of the specific nucleotide – cyclic guanosine monophosphate (cGMP) necessary to relax the muscles of the hollow body, resulting in an increased blood flow in the penis.

Indications for the use of the drug are not only erectile dysfunction, but also pulmonary hypertension. The drug expands the vessels in the respiratory organs and reduces pressure therein. Thanks to this medicine, respiratory problems in people with this disease are considerably reduced and shortness of breath is also reduced. 

In addition, the drug’s ability to reduce pressure has been proven. However, this effect only lasts during the tablet operation and buying sildenafil after completion, the pressure is restored to the previous values.

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Application functions

The Sildenafil medication should preferably be taken one hour before intimacy. Do not be afraid that the drug will work prematurely, because the effect of the use in men only starts with natural sexual arousal.

If there is no desire for a partner then – as it should be – no erection will occur. If you have to choose between 25 mg, 50 mg or 100 mg doses, you should consult a specialist who prescribes the required concentration of the substance based on the individual characteristics of the patient.

As a general rule, 25-50 mg will be sufficient as a starting dose. Instructions for use of the drug include instructions on the maximum daily dose, which should not exceed 100 mg. It is not recommended to take the maximum amount the first time. It is recommended to rinse the tablets with a large amount of water because they have a specific taste.

The duration of the cure is 5 hours effective duration of action is between 4-6 hours. The effect of taking medication remains with men throughout sexual contact and it supports the natural ability to perform sexual intercourse healthily and energetically. In the case of repeated desire for intimacy before the appearance of an erection, no additional use of the drug is required.

Tablets can be consumed on a full or empty stomach, but it should be taken into account that the intake of this medicine, after consuming fatty foods, will take 20-25 minutes longer. Viagra and its generic variants (Sildenafil Medan, Maxigra, etc.) can be combined with a moderate dose of alcohol.

Application for pulmonary hypertension

It is not convenient to use 100mg tablets for this application, since the recommended dose is usually 25mg 3 times a day – at intervals of 7-8 hours. There are tablets with smaller doses that are better suited for this.

If someone tolerates the medicine well, the dosage can be increased to 50mg at a time. however, it is not necessary or recommended to use more than 100 mg per day without doctor’s instructions.

Older people should take this medicine at a dose of only 25 mg at a time. The same applies to men and women who suffer from kidney and liver disorders. If the medicine is poorly tolerated by the body, then a daily dose of 100 mg is not recommended. 50mg per day is wiser, spread over 2 doses of 25mg.

Sildenafil for women

Have recently Viagra and his analogues can increasingly be used to eliminate intimate problems, not only for men, but also for fair sex. Their effectiveness in women has been proven, even at menopause and after removal of the uterus.

Through the use of drugs, such effects were found in the fair sex:

  • increased libido;
  • sensuality enhancement;
  • reduction in the time during which excitement occurs;
  • increased moisture content of the vagina;
  • improvement of blood circulation in the genital area;
  • increased sensitivity in erogenous zones;
  • increased duration of the orgasm;
  • elimination of frigidity;
  • increased sexual desire in older women;
  • increased endurance with intimacy.

Tablets have a complex effect on women because, in addition to intensifying excitement, they stimulate sexual attraction to the sexual partner. Increased blood flow in the pelvic organs contributes to a greater sensitivity and clarity of feelings during intimacy. Thanks to this preparation, the vagina is naturally much better moistened, therefore its use is recommended if the vagina dehydrates.

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Contra

Before taking Sildenafil, you should consult a specialist buying sildenafil because the instructions for use of the medication contain many contraindications that are dangerous to ignore. There are a number of diseases against which Viagra and similar medicines are prohibited. Among them the following pathologies:

  • Angina pectoris
  • Liver disease in severe form
  • Stenosis of the aorta
  • Cardiomyopathy
  • Hypotension
  • Heart failure
  • Heart attack or stroke
  • Some retinal pathologies
  • Age up to 18 years
  • Individual intolerance of the drug and allergy to its components

In addition to the diseases described above, there are relative contraindications for taking medication. In the following pathologies, admission can only be allowed after permission from a doctor. These include:

  • Leukemia
  • Anomalies in the structure and deformation of the penis
  • Anemia sickle cell type
  • Myeloma
  • Low platelet count in the blood
  • Diseases where blood loss may occur (for example, an ulcer in an acute form)

In order to use the drug effectively without the occurrence of negative consequences, the possible side effects and disadvantages must be carefully examined.

Ventricular extrasystole and use of medication

For people who have had problems with heart problems, use has an increased risk and should only be used under supervision. Ventricular extrasystole is another pathology where applying Sildenafil Buying can be dangerous. It is a disease that is accompanied by cardiac arrhythmias and the appearance of extra impulses in the heart. Pathology is associated with the following symptoms:

  • Unusual sensations in the region of the heart (for example, loud unstable strokes)
  • Dizziness
  • Shortness of breath
  • Feeling of fear, fear

There are signs of lung disease similar to hypertension, where sildenafil appears. Possibly accompanied by shortness of breath and hypertension. However, before you use the medicine to treat this symptom, you must be diagnosed and treated by a specialist. This will be able to easily determine the cause of the unpleasant symptoms.